西蜀颜颜 发表于 2025-5-9 18:21:53

男生女生们,不要让HPV成为你们感情的隐患

<section data-role="outer" class="article135" label="edit by 135editor"><section class="_135editor" data-role="paragraph"><p style="text-align:justify; line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 当我们谈论HPV(人乳头瘤病毒)时,很多人的第一反应可能是:“哦,那是女生要担心的事,跟男生没关系。”</span></p><p style="text-align:justify; line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 但其实,HPV可只不是“女生专属”哦!它对你和身边的他可能也有影响,甚至可能成为你们之间的“隐形炸弹”。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="139453"><section style="margin: 10px auto;" class=""><section style="border: 1px solid #ffeb49;padding: 4px;margin: 0 10px;box-sizing:border-box;" class=""><section style="width: 100%;max-width: 100% !important;box-sizing:border-box;" data-width="100%" class=""><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/qY8ShQmm_QIfA.png?auth_key=1746979199-0-0-4faa97acf19f62fb4e535d54172871dc" data-width="100%" draggable="false" data-ratio="0.5625" alt="图片1.png" data-w="1200"/></section></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:justify; line-height: 2em;"><span style="font-size:15px;"><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;">&nbsp; &nbsp; &nbsp; 据2023年ICO/IARC中国HPV相关疾病报告显示:中国有5.824亿15岁及以上女性面临患宫颈癌的风险1.!值得注意的是,高危型HPV不仅是宫颈癌的主要诱因,其致癌作用同样体现在肛门癌中。一项中国HPV流行病学研究显示,88%的肛门癌也可能归因于HPV感染2a。</span><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;"></span></span></p><p style="text-align:justify; line-height: 2em;"><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 在面对HPV时,你们不仅仅是“爱人”,更是并肩作战的“战友”。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/2zGKUE4X_r4z4.png?auth_key=1746979199-0-0-487bd6256a2f1d24e2b0096e9ce66087" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片2.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="line-height: 2em;"><strong><span style="font-size:15px;"><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;">1.&nbsp;HPV的“多重”机制--使其广泛传播</span></span></strong></p><p style="text-align:left; line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; HPV主要通过性接触传播。此外,HPV的感染还可通过母婴传播以及直接接触传播,如皮肤黏膜接触3。比如酒店的浴巾毛巾4、公共浴室5、泳池6,b等清洁消毒不到位接触皮肤黏膜也可能会传染HPV。</span></p><p style="line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; HPV病毒是一种比较顽强的病毒,耐寒不耐热,高温消毒和2%戊二醛消毒可灭活,但对酒精不敏感3。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/vUbjuWPI_KP3Z.png?auth_key=1746979199-0-0-914d7f2339e4e52ae93aa25b0548b7b8" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片4.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="line-height: 2em;"><strong><span style="font-size:15px;"><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;">2.&nbsp;HPV的“隐形”特性—使其持续感染</span></span></strong></p><p style="line-height: 2em;"><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 一项2014年基于美国人群的模型研究估算7,c,在HPV疫苗上市前,至少有1位异性伴侣的人一生中,女性一生中感染HPV 的平均概率为84.6%,男性为91.3%。</span></p><p style="line-height: 2em;"><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 大多数男性和女性的HPV感染是无症状的8,</span><strong><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">这意味着,即使你和你的伴侣看起来都很健康,也可能已经携带了病毒。</span></strong><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">因此,男性进行HPV筛查是必要的。然而,目前仅强调对女性进行标准化的HPV筛查,</span><strong><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">暂无针对男性的HPV常规筛查项目9。</span></strong></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/WeW4GAjr_QH3R.png?auth_key=1746979199-0-0-b96b73d8b7bc062d52c6fdb720666963" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片5.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:justify; line-height: 2em;"><span style="font-size:15px;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;">&nbsp; &nbsp; &nbsp; 一项在健康男性进行的关于HPV自然演变的纵向研究发现,感染HPV的男性在3.7年内再次感染同一型别HPV的重复感染率达24.6%10,d。一项高危型人乳头瘤病毒感染女性的配偶病毒跟踪检测结果分析显示,感染者配偶感染高危型HPV后,1年内的病毒自然清除率仅为31.82%,低于女性11,e。这种“反复感染-低清除”的循环,可能导致男性长期携带病毒,并持续威胁伴侣健康。</span><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;"></span></span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/CFceBMfO_rvPD.png?auth_key=1746979199-0-0-8a586b8e55e64a458727ba34941de200" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片6.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:justify; line-height: 2em;"><span style="font-size:15px;"><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;">&nbsp; &nbsp; &nbsp; 一项在健康男性进行的关于HPV自然演变的纵向研究发现,感染HPV的男性在3.7年内再次感染同一型别HPV的重复感染率达24.6%10,d。一项高危型人乳头瘤病毒感染女性的配偶病毒跟踪检测结果分析显示,感染者配偶感染高危型HPV后,1年内的病毒自然清除率仅为31.82%,低于女性11,e。这种“反复感染-低清除”的循环,可能导致男性长期携带病毒,并持续威胁伴侣健康。</span><span style="font-weight: 400; color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px;"></span></span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/ZqjBCpYf_Gu2J.png?auth_key=1746979199-0-0-654eaf6e7036eac5a679e7ecff561c56" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片7.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:justify;line-height: 2em;"><strong><span style="font-size:15px;"><span style="color: #3f3f3f; text-shadow: none; letter-spacing: 1px;">3.&nbsp;HPV的“交互”作用--使其更易传播</span></span></strong></p><p style="text-align:justify; line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 与此同时,一项基于中国人群的队列研究发现,若一方持续感染HPV,</span><strong><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">伴侣间的HPV传播风险增加1.25倍;</span></strong><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">若感染的是高危型HPV,</span><strong><span style="color: rgb(63, 63, 63); text-shadow: none; letter-spacing: 1px; font-size: 15px;">伴侣间传播风险则增加5.95倍12,f。</span></strong></p></section><section class="_135editor" data-role="paragraph"><p style="text-align:justify; line-height: 2em;"><span style="font-size:15px;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;">&nbsp; &nbsp;</span><strong><span style="color: #3f3f3f; text-shadow: none; letter-spacing: 1px;"> &nbsp; 因此,仅选择性地为女性接种疫苗并不能为男性提供足够的保护13!!!</span></strong><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;">此外,男性持续感染HPV后将增加伴侣感染风险,并可能增加伴侣患宫颈癌的风险9。</span><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;"></span></span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/qZrzzTZa_JdcV.png?auth_key=1746979199-0-0-a1b2490da6d0a38abd4852b781b82bfe" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片8.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:center; line-height: 2em;"><strong><span style="font-size:15px;"><span style="color: #3f3f3f; text-shadow: none; letter-spacing: 1px;">HPV的感染,可能带来的严重后果</span></span></strong></p><p style="line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; HPV感染后大多可被免疫机制自行清除,但是持续感染HPV有可能会导致多种疾病3 。一项2016年的研究显示2,a ,几乎所有的宫颈癌,约90%的肛门癌有可能归因于HPV感染。&nbsp;低危型HPV感染还可能引起尖锐湿疣(生殖器疣)3,90%的尖锐湿疣可能归因于相关型别HPV感染14,15,此病容易复发15。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/jUYCwrK2_RTrm.png?auth_key=1746979199-0-0-14652a67cc37d68300e15a48d8f554c9" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片9.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:center; line-height: 2em;"><strong><span style="font-size:15px;"><span style="line-height: 200%; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;font-family:微软雅黑;">男女统一战线,共御HPV感染</span></span></strong></p><p style="line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; 根据2023年中国《子宫颈癌综合防控指南(第2版)》提出的三级预防策略与《人乳头瘤病毒疫苗临床应用中国专家共识》,接种HPV疫苗是预防HPV相关疾病的有效方法之一16,17。与此同时,在日常生活中避免共用个人卫生用品、***中使用安全套,定期体检等措施均可预防HPV感染18。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/ROg4zDBD_qvDQ.png?auth_key=1746979199-0-0-37d1405711503fc881efe97f7d98cab8" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="图片10.png" data-w="690"/></section></section></section><section class="_135editor" data-role="paragraph"><p style="text-align:center; line-height: 2em;"><strong><span style="font-size:15px;"><span style="line-height: 200%; color: #3f3f3f; text-shadow: none; letter-spacing: 1px;font-family:微软雅黑;">男女共防HPV,保护你和你爱的人</span></span></strong></p><p style="line-height: 2em;"><span style="font-weight: 400; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">&nbsp; &nbsp; &nbsp; HPV防控本质上是关于关系的医学。正如世界卫生组织所倡导的:消除宫颈癌不是女性独自的征程,而是需要全人类携手跨越的峡谷。 HPV感染不分性别,预防HPV不分男女!男女共防HPV,是对健康共同体理念最有力的践行。阻断HPV传播——需要你、我、他的共同力量。</span></p></section><section class="_135editor" data-tools="135编辑器" data-id="154519"><section style="margin: 10px auto; display: flex; align-items: flex-end;"><section style="width: 100%;max-width:100% !important;box-sizing:border-box;" class="" data-width="100%"><img style="width: 100%; display: block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://bexp.135editor.com/files/users/1028/10285417/202505/nYJFU7Of_8rHg.png?auth_key=1746979199-0-0-0113ba7bfacf4d9b9bde9bb179aa6ac8" data-width="100%" draggable="false" data-ratio="0.6753623188405797" alt="微信截图_20250509181851.png" data-w="690"/></section></section></section><section class="_135editor" data-tools="135编辑器" data-id="96817"><section style="margin: 5px auto 10px;" class=""><section class="assistant" style="width:150px;margin:0px auto;box-sizing:border-box;transform: rotate(0deg);-webkit-transform: rotate(0deg);-moz-transform: rotate(0deg);-o-transform: rotate(0deg);"><img style="width:100%;display:block;vertical-align:baseline;box-sizing:border-box;max-width:100% !important;" src="https://image2.135editor.com/cache/remote/aHR0cHM6Ly9tbWJpei5xbG9nby5jbi9tbWJpel9naWYvN1FSVHZrSzJxQzVIWVp4aWJxYXA4TjFPZ3h0YlBNTkliaE83S1daejlxSDVsbDlGR0JlaWNGVWdBbjc1ekF0U295SmlhZTc1dGlhQlE2QXp3M29vQTI5MXZRLzA/d3hfZm10PWdpZg==" data-width="100%" draggable="false" data-ratio="0.2" data-w="500"/></section><section style="margin-top:-16px;display:flex;justify-content: center;align-items: center;border:1px dashed #76c7eb;border-radius:15px ;padding:2em 0px;box-sizing:border-box;" class=""><section class="assistant" style="width:30px;height:30px;overflow:hidden;border-radius:100%;border:1px solid #76c7eb;box-sizing:border-box;transform: rotate(-90deg);-webkit-transform: rotate(-90deg);-moz-transform: rotate(-90deg);-o-transform: rotate(-90deg);"><img style="width:30px;display:block;vertical-align:baseline;box-sizing:border-box;" src="https://image2.135editor.com/cache/remote/aHR0cHM6Ly9tbWJpei5xbG9nby5jbi9tbWJpel9naWYvN1FSVHZrSzJxQzVIWVp4aWJxYXA4TjFPZ3h0YlBNTkliaWJtS2V2UEp1YmVWZ2NDeDZGNzdDVGgwQUdFZ2ZYV2dWUVhEMExFV053RzVWZVZBVmc4UlNUUS8wP3d4X2ZtdD1naWY=" draggable="false" data-ratio="1" data-w="200"/></section><section style="width:120px;border:1px solid #76c7eb;margin:0px 1em;box-sizing:border-box;" class=""><img style="width: 118px; 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margin: 0px; padding: 0px; box-sizing: border-box !important; overflow-wrap: break-word !important; cursor: text; color: #333333; font-size: 17px;      text-align: center;      caret-color: #ff0000;   text-decoration-thickness: initial;;font-family:mp-quote, -apple-system-font, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;"><span style="max-inline-size: 100%; margin: 0px; padding: 0px; box-sizing: border-box !important; overflow-wrap: break-word !important; cursor: text; color: #3f3f3f; text-shadow: none; letter-spacing: 1px; font-size: 15px;">如需预约,请扫描以下二维码</span></strong></section></section></section></section><section class="_135editor" data-role="paragraph"><p><span style=";font-size:12px;font-family:微软雅黑;"><span style="font-family:微软雅黑;"><br/></span></span></p><p><span style=";font-size:12px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">参考文献:</span></span></p><p><span style="font-size:10px;font-family:微软雅黑;">1.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">China Human Papillomavirus and Related Cancers, Fact Sheet 2023 (2023-03-10): https://hpvcentre.net/statistics/reports/CHN_FS.pdf </span></p><p><span style="font-size:10px;font-family:微软雅黑;">2.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">元玫雯</span>, 等. 2016年中国归因于人乳头瘤病毒感染的肿瘤发病与死亡分析.中华流行病学杂志. 2022, 43(5): 702-708.</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">a.</span></span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;<span style="font-family:微软雅黑;">研究设计:该研究为一项中国</span>HPV流行病学研究,旨在分析2016 年我国归因于人乳头瘤病毒(HPV)感染的肿瘤发病和死亡情况。结合肿瘤发病率、死亡率、全国人口数及人群归因分值(PAF)计算2016年全国不同地区、不同年龄及男性和女性人群归因于HPV感染的肿瘤发病数和死亡数。</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:</span>2016年全国有124,772例(6.32/10万)肿瘤新发病例归因于HPV感染,其中宫颈癌和肛门癌的归因分值为100%和88%。</span></p><p><span style="font-size:10px;font-family:微软雅黑;">3.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">中华预防医学会疫苗与免疫分会</span>.子宫颈癌等人乳头瘤病毒相关疾病免疫预防专家共识. 中华预防医学杂志,2019,53(8):761-803.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">4.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Wei F, Yin K, Wu X, Lan J, Huang S, Sheng W, Zhao J, Su Y, Wang Y, Li Y, Li R, Zhang J, Li M, Wu T,</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Xia N. Human papillomavirus prevalence and associated factors in women and men in south China: a</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">population-based study. Emerg Microbes Infect. 2016 Nov 23;5(11):e119.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">5.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Zhao FH, Forman MR, Belinson J, Shen YH, Graubard BI, Patel AC, Rong SD, Pretorius RG, Qiao YL. Risk</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">factors for HPV infection and cervical cancer among unscreened women in a high-risk rural area of</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">China. Int J Cancer. 2006 Jan 15;118(2):442-8.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">6.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">La Rosa G, Della Libera S, Petricca S, Iaconelli M, Briancesco R, Paradiso R, Semproni M, Di Bonito</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">P, Bonadonna L. First detection of papillomaviruses and polyomaviruses in swimming pool waters:</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">unrecognized recreational water-related pathogens? J Appl Microbiol. 2015 Dec;119(6):1683-91.</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">b</span></span><span style=";font-size:10px;font-family:微软雅黑;">.</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;<span style="font-family:微软雅黑;">研究设计:</span></span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">一项环境流行病学研究,对游泳池中的人类肠道病毒(腺病毒、诺如病毒和肠病毒)以及非肠道病毒(乳头瘤病毒和多瘤病毒,包括</span>BK、JC、KI、WU 和Merkel 细胞)进行了检测。同时评估了细菌学参数。分析的泳池水符合微生物质量标准,未检测到肠道病毒。研究旨在检查室内和室外游泳池中病毒污染的范围。</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:分析的泳池水符合微生物质量标准,未检测到肠道病毒。然而,乳头瘤病毒(</span>HPV8、12、23、25、120及未分类的HPVs)和多瘤病毒(JC 和Merkel 细胞多瘤病毒)在9 个(64%)样本中被检测到。通过定量实时PCR检测,泳池水中的HPV DNA 拷贝数范围为1.27E+04 至1.13E+05/10L。</span></p><p><span style="font-size:10px;font-family:微软雅黑;">7.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Chesson HW, et al. Sex Transm Dis. 2014; 41(11):660–664.</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">c</span></span><span style=";font-size:10px;font-family:微软雅黑;">. 研究设计:该研究建立了一个简单模型,因为没有研究跟踪整个生命周期来估计 HPV 感染的累积发生率,所以只能根据现有证据来估计终生获得 HPV 的概率。主要基于人群一生中性伴侣数量的分布以及每个性伴侣感染HPV的概率,来估算美国人在HPV疫苗上市前一生中感染HPV的概率。该研究对两个年龄段人群(首次性行为到44岁;45岁到70岁)感染HPV的概率进行了估算,第一年龄阶段感染HPV的概率是根据直到44岁的性伴侣数量以及性伴侣HPV感染情况进行研究,第二年龄阶段的HPV感染率是使用每年HPV感染概率的估计值进行计算。44岁之前没有异性伴侣的人被排除在研究之外。</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:在至少有一个异性伴侣的人中,女性感染</span>HPV的终生患病率为84.6%(53.6%-95.0%),男性为91.3%(69.5%-97.7%)。</span></p><p><span style="font-size:10px;font-family:微软雅黑;">8.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">ONE-IN-THREE-MEN-WORLDWIDE-ARE-INFECTED-WITH-GENITAL-HUMAN-PAPILLOMAVIRUS.Access</span><span style=";font-size:10px;font-family:微软雅黑;">&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">on.https://www.who.int/news/item/01-09-2023-one-in-three-men-worldwide-are-infected-with-genital-human-papillomavirus</span></p><p><span style="font-size:10px;font-family:微软雅黑;">9.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Zou K, et al. Front Cell Infect Microbiol. 2022 Nov 24;12:1077651.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">10.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Pamnani SJ, et al. J Infect Dis. 2018 Sep 8;218(8):1219-1227.</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">d</span></span><span style=";font-size:10px;font-family:微软雅黑;">.研究设计:HIM研究是针对美国、巴西和墨西哥健康男性开展的一项HPV自然史研究。本研究纳入4123HIM研究中受试者的生殖器DNA样本,旨在评估九价HPV疫苗中所含9种HPV型别在男性生殖器的重复感染率,并调查与复发感染相关的因素。每6个月对男性进行一次随访,平均随访3.7年。</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:</span>31%的流行感染和20%的偶发感染出现复发。在流行感染中,HPV 52、45、16、58和6复发率最高,而在偶发感染中,HPV类型58、52、18、16和11复发率最高。新的性伴侣(男性或女性)、与女性伴侣的***频率和HPV-6、16、31和58感染复发有关。</span></p><p><span style="font-size:10px;font-family:微软雅黑;">11.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">赵学英</span>,刘学伟.高危型人乳头瘤病毒感染女性的配偶病毒跟踪检测结果分析.国际检验医学杂志,2017,38(17):2339-2341.</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">e</span></span><span style=";font-size:10px;font-family:微软雅黑;">. 研究设计:一项研究,旨在探讨高危型HPV感染女性的配偶病毒感染状况、自然消退情况及夫妻型别吻合率。对2013年1月-2015年10月某院246例生殖道高危HPV感染女性的配偶进行阴茎头上皮细胞和尿道口分泌物的病毒跟踪检测,检测间隔为1年。</span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:感染者配偶</span>1年病毒自然清除率为31.82%(35/110)。阳性检出率初始检测为44.72%(110/246)。</span></p><p><span style="font-size:10px;font-family:微软雅黑;">12.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">Liu M, et al. Sci Rep. 2015 ;5:10986.</span></span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">f.研究设计:一项2007-2009年在中国河南省安阳市农村开展的基于人群的食管癌队列研究(AECCS)。根据整群抽样的方法,选取安阳市农村的 9个村作为目标村。本研究采用了一个子队列,其中包括 9个目标村庄中的 3个。主要研究目的为评估夫妻人群中 HPV阳性一致率、传播率及相关风险因素。研究对象为 25-65岁中国农村夫妻,样本量 874对,研究时长 2009年~2013年。此项研究中评估的 HPV传播因素包括研究对象的平均年龄、平均性伴侣数、每周***频次,以及教育水平、工作类型、HPV持续感染情况。</span></span></p><p><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">研究结果:夫妇间</span><span style="font-family:微软雅黑;">HPV任一型别、致癌型别、非致癌型别感染的一致性分别为15.52%、16.18%、10.41%。对于致癌型别,男性向女性传播的风险显著高于女性向男性传播的风险。对于非致癌型,男性向女性传播的风险显著低于女性向男性传播。年轻夫妇、HPV持续感染、性伴侣数量较多、***频率较高与夫妻间HPV相互传播呈正相关。</span></span></p><p><span style="font-size:10px;font-family:微软雅黑;">13.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">Baker, P., Prue, G., Rae, J., Winterflood, D., & Favato, G. (2019, January 15). Jabs for the Boys. International Journal of Mens Social and Community Health. University of Toronto Press Inc. (UTPress). http://doi.org/10.22374/ijmsch.v2i1.18</span></p><p><span style="font-size:10px;font-family:微软雅黑;">14.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;">ANOGENITAL WARTS, SEXTUALLY TRANSMITTED INFECTIONS TREATMENT GUIDELINES, 2021. Access on. https://www.cdc.gov/std/treatment-guidelines/anogenital-warts.htm</span></p><p><span style="font-size:10px;font-family:微软雅黑;">15.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">中华医学会皮肤性病学分会</span>,中国医师协会皮肤科医师分会,中国康复医学会皮肤性病委员会.中国尖锐湿疣临床诊疗指南(2021完整版).中国皮肤性病学杂志,2021,35(04):359-374.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">16.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">李双</span>,李明珠,丛青,等.人乳头瘤病毒疫苗临床应用中国专家共识.中国妇产科临床杂志,2021,22(02):225-234.</span></p><p><span style="font-size:10px;font-family:微软雅黑;">17.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">王临虹</span>,赵更力.子宫颈癌综合防控指南(第2版).北京:人民卫生出版社.2023.6</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">.</span></span></p><p><span style="font-size:10px;font-family:微软雅黑;">18.&nbsp;</span><span style=";font-size:10px;font-family:微软雅黑;"><span style="font-family:微软雅黑;">黄莉荣</span>.HPV并非女性“专属”,男性也要防感染.健康生活,2024,(10):10-11.</span></p></section></section><p><br/></p><link rel="stylesheet" href="https://bbs.xishuw.com/source/plugin/wcn_editor/public/wcn_editor_fit.css?v133_ZrA" id="wcn_editor_css"/>

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腰腿痛终点站 发表于 4 天前

说的很对,得了这个病真的不好治,我老婆得了这个病花了不少钱,最后在一个女中医那里看好的前后差不多八个月,
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